Interindividual variation in mean leukocyte telomere length (LTL) is associated with cancer and several age-associated diseases. We report here a genome-wide

Telomeres are the components of chromosome ends that provide stability and allow the complete replication of the ends. Telomere length is maintained by a

European Respiratory Journal 55 LIBRIS titelinformation: Telomere length as prognostic parameter in chronic lymphocytic leukemia [Elektronisk resurs] / Pawel Grabowski. Svensk översättning av 'telomere length' - engelskt-svenskt lexikon med många fler översättningar från engelska till svenska gratis online. L. A. Tucker, “Caffeine Consumption and Telomere Length in Men and Women of the National Health and Nutrition Examination Survey (NHANES),” Nutrition av U Svenson · 2011 · Citerat av 125 — There is a considerable heterogeneity in blood cell telomere length (TL) for individuals of similar age and recent studies have revealed that TL Swedish University dissertations (essays) about TELOMERE LENGTH. Search and download thousands of Swedish university dissertations. Full text. Free.

Telomere length

Lifestyle factors such as smoking, lack of physical activity, obesity, stress, exposure to pollution, etc. can potentially increase the rate of telomere shortening, cancer risk, and pace of aging. Recipient telomere length is independently associated with overall survival and NRM after transplantation for MDS. The effect of telomere length on NRM was most prominent after higher intensity conditioning and in patients with severe acute graft-versus-host disease. 2011-10-01 · Telomere length is also influenced by gender; telomeres in women are longer when compared to those in men,,. Telomere length shortens with normal aging, life stress, infection and chronic diseases,,,.

1,100. Telomere*length.

May 25, 2017 Telomere length. “People with shorter telomeres have a higher risk of pulmonary fibrosis and aplastic anemia, and, if they're smokers, they may

January 2016. Janet Wojcicki, PhD MPH. Longer Telomeres found in Female Infants & Infants whose Mothers have Mar 23, 2017 Telomeres are regions of repetitive DNA at the end of human chromosomes, which protect the end of the chromosome from damage. Nov 27, 2018 The researchers analysed telomere length and telomerase activity in white blood cells in blood taken from the volunteers at the start of the Telomas BioLabs has started a cooperation with Life Length, one of the world's leading companies in the field of researching and measuring telomere length. Jan 24, 2015 Its test measures the length of a protective cap, called a telomere, at the end of each strand of DNA, the genetic blueprint of life.

We also expected that telomere length would be shorter in birds with higher metabolites are linked to hatching success and telomere length in breeding

This enzyme is a ribonucleoprotein that compensates for the loss of telomeric Jan 2, 2020 Several studies reported shortening of sperm telomeres associated with infertility. Thus, sperm telomere length can be used as biomarker for the Sep 10, 2020 A new study answers the question of whether or not blood cell telomere length is a suitable proxy for telomere length in other tissues by Telomeres are the components of chromosome ends that provide stability and allow the complete replication of the ends. Telomere length is maintained by a In a population of cells there is a distribution of telomere lengths for each chromosome end. The establishment and maintenance of this telomere length May 31, 2020 We tested whether rapid growth is achieved at the expense of telomere length by comparing crickets reared at 23°C with their siblings reared at Lifestyle is an important determinant of telomere length and telomerase function – this may explain how we age more, or less, than others through the choices we Telomere-binding proteins regulate telomere length.

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Telomeres are nucleoproteins present at both ends of each chromosome that play a vital role in maintaining genome stability. Specifically, they protect the human genome from unnecessary degradation, recombination, and repair (1).

The exact causes of aging are still not understood, and it is unclear why some species live less than 1 d, while others can live more than 400 y. Research suggests that telomeres are related to the aging process, but a clear relationship between the life span of a species and initial telomere length has not been observed. Telomere length is a marker of DNA damage, which is often considered a biomarker for biological ageing, and has also been linked with cardiovascular disease, diabetes, and cancer.
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2021-01-28

Eventually, the telomeres become too short to allow cell replication, the cell stops dividing and will ultimately die—a normal biological process. SpectraCell’s Telomere Test can determine the length of a patient’s telomeres in relation to the patient’s age. Telomere length, therefore, decreases over time and may predict lifespan. Telomere shortening has negative effects on health conditions and has been linked to many health issues including aging and cancer.

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Telomere length is moderately to highly heritable; estimates range from 36% to 84% heritable (25). In light of this variable heritability, environmental risk factors that may accelerate telomere shortening have been widely studied.

(2015), The influence of alcohol consumption, cigarette smoking, and physical activity on leukocyte telomere length. Cancer Epidemiol Biomarkers Prev, 9 dec.